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Relevance of PepT1 in the Intestinal Permeability and Oral Absorption of Cefadroxil
PURPOSE: To determine the contribution of intestinal PepT1 on the permeability and oral absorption of the β-lactam antibiotic drug cefadroxil. METHODS: The effective permeability (P(eff)) of cefadroxil was evaluated in wild-type and PepT1 knockout mice following in situ single-pass intestinal perfus...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3596500/ https://ncbi.nlm.nih.gov/pubmed/23224978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-012-0937-8 |
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