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Relevance of PepT1 in the Intestinal Permeability and Oral Absorption of Cefadroxil

PURPOSE: To determine the contribution of intestinal PepT1 on the permeability and oral absorption of the β-lactam antibiotic drug cefadroxil. METHODS: The effective permeability (P(eff)) of cefadroxil was evaluated in wild-type and PepT1 knockout mice following in situ single-pass intestinal perfus...

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Bibliografske podrobnosti
Main Authors: Posada, Maria M., Smith, David E.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596500/
https://ncbi.nlm.nih.gov/pubmed/23224978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-012-0937-8
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