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Mechanism for Calcium Ion Sensing by the C2A Domain of Synaptotagmin I
The C2A domain is one of two calcium ion (Ca(2+))- and membrane-binding domains within synaptotagmin I (Syt I), the identified Ca(2+) sensor for regulated exocytosis of neurotransmitter. We propose that the mechanistic basis for C2A's response to Ca(2+) and cellular function stems from marginal...
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| Hoofdauteurs: | , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
The Biophysical Society
2012
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3400769/ https://ncbi.nlm.nih.gov/pubmed/22853901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.05.051 |
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