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Permutation-based approaches do not adequately allow for linkage disequilibrium in gene-wide multi-locus association analysis
Additional information about risk genes or risk pathways for diseases can be extracted from genome-wide association studies through analyses of groups of markers. The most commonly employed approaches involve combining individual marker data by adding the test statistics, or summing the logarithms o...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3400741/ https://ncbi.nlm.nih.gov/pubmed/22317971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2012.8 |
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