Copy number, linkage disequilibrium and disease association in the FCGR locus

The response of a leukocyte to immune complexes (ICs) is modulated by receptors for the Fc region of IgG (FcγRs), and alterations in their affinity or function have been associated with risk of autoimmune diseases, including systemic lupus erythematosus (SLE). The low-affinity FcγR genomic locus is...

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محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Niederer, Heather A., Willcocks, Lisa C., Rayner, Tim F., Yang, Wanling, Lau, Yu Lung, Williams, Thomas N., Scott, J. Anthony G., Urban, Britta C., Peshu, Norbert, Dunstan, Sarah J., Hien, Tran Tinh, Phu, Nguyen Hoan, Padyukov, Leonid, Gunnarsson, Iva, Svenungsson, Elisabet, Savage, Caroline O., Watts, Richard A., Lyons, Paul A., Clayton, David G., Smith, Kenneth G.C.
التنسيق: Artigo
اللغة:Inglês
منشور في: Oxford University Press 2010
الموضوعات:
Association Studies Articles
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908468/
https://ncbi.nlm.nih.gov/pubmed/20508037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq216
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