Copy number, linkage disequilibrium and disease association in the FCGR locus

The response of a leukocyte to immune complexes (ICs) is modulated by receptors for the Fc region of IgG (FcγRs), and alterations in their affinity or function have been associated with risk of autoimmune diseases, including systemic lupus erythematosus (SLE). The low-affinity FcγR genomic locus is...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Niederer, Heather A., Willcocks, Lisa C., Rayner, Tim F., Yang, Wanling, Lau, Yu Lung, Williams, Thomas N., Scott, J. Anthony G., Urban, Britta C., Peshu, Norbert, Dunstan, Sarah J., Hien, Tran Tinh, Phu, Nguyen Hoan, Padyukov, Leonid, Gunnarsson, Iva, Svenungsson, Elisabet, Savage, Caroline O., Watts, Richard A., Lyons, Paul A., Clayton, David G., Smith, Kenneth G.C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2010
Pynciau:
Association Studies Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908468/
https://ncbi.nlm.nih.gov/pubmed/20508037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq216
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