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FCGR2C genotyping by pyrosequencing reveals linkage disequilibrium with FCGR3A V158F and FCGR2A H131R polymorphisms in a Caucasian population

The FCGR3A-V158F and FCGR2A-H131R polymorphisms are associated with clinical responses to therapeutic mAbs and with immune thrombocytopenic purpura (ITP). The FCGR2C-ORF/STOP polymorphism, controlling FcγRIIC expression on natural killer cells and therefore FcγRIIC-mediated antibody dependent cell-m...

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Detalhes bibliográficos
Main Authors: Lejeune, Julien, Piègu, Benoît, Gouilleux-Gruart, Valérie, Ohresser, Marc, Watier, Hervé, Thibault, Gilles
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3502245/
https://ncbi.nlm.nih.gov/pubmed/23032993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.22287
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