Evidence of Inbreeding Depression on Human Height

Stature is a classical and highly heritable complex trait, with 80%–90% of variation explained by genetic factors. In recent years, genome-wide association studies (GWAS) have successfully identified many common additive variants influencing human height; however, little attention has been given to...

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Autori principali: McQuillan, Ruth, Eklund, Niina, Pirastu, Nicola, Kuningas, Maris, McEvoy, Brian P., Esko, Tõnu, Corre, Tanguy, Davies, Gail, Kaakinen, Marika, Lyytikäinen, Leo-Pekka, Kristiansson, Kati, Havulinna, Aki S., Gögele, Martin, Vitart, Veronique, Tenesa, Albert, Aulchenko, Yurii, Hayward, Caroline, Johansson, Åsa, Boban, Mladen, Ulivi, Sheila, Robino, Antonietta, Boraska, Vesna, Igl, Wilmar, Wild, Sarah H., Zgaga, Lina, Amin, Najaf, Theodoratou, Evropi, Polašek, Ozren, Girotto, Giorgia, Lopez, Lorna M., Sala, Cinzia, Lahti, Jari, Laatikainen, Tiina, Prokopenko, Inga, Kals, Mart, Viikari, Jorma, Yang, Jian, Pouta, Anneli, Estrada, Karol, Hofman, Albert, Freimer, Nelson, Martin, Nicholas G., Kähönen, Mika, Milani, Lili, Heliövaara, Markku, Vartiainen, Erkki, Räikkönen, Katri, Masciullo, Corrado, Starr, John M., Hicks, Andrew A., Esposito, Laura, Kolčić, Ivana, Farrington, Susan M., Oostra, Ben, Zemunik, Tatijana, Campbell, Harry, Kirin, Mirna, Pehlic, Marina, Faletra, Flavio, Porteous, David, Pistis, Giorgio, Widén, Elisabeth, Salomaa, Veikko, Koskinen, Seppo, Fischer, Krista, Lehtimäki, Terho, Heath, Andrew, McCarthy, Mark I., Rivadeneira, Fernando, Montgomery, Grant W., Tiemeier, Henning, Hartikainen, Anna-Liisa, Madden, Pamela A. F., d'Adamo, Pio, Hastie, Nicholas D., Gyllensten, Ulf, Wright, Alan F., van Duijn, Cornelia M., Dunlop, Malcolm, Rudan, Igor, Gasparini, Paolo, Pramstaller, Peter P., Deary, Ian J., Toniolo, Daniela, Eriksson, Johan G., Jula, Antti, Raitakari, Olli T., Metspalu, Andres, Perola, Markus, Järvelin, Marjo-Riitta, Uitterlinden, André, Visscher, Peter M., Wilson, James F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400549/
https://ncbi.nlm.nih.gov/pubmed/22829771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002655
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