Caricamento...
Pharmacokinetic similarity of biologics: analysis using nonlinear mixed-effects modeling
Our objective was to show with two examples that a pharmacokinetic (PK) similarity analysis can be performed with nonlinear mixed effects models (NLMEM). We used two studies comparing different biosimilars: a three-way crossover trial on somatropin and a parallel group trial on epoetin alpha. For bo...
Salvato in:
| Autori principali: | , , , , , , |
|---|---|
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Pub. Group
2012
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3400548/ https://ncbi.nlm.nih.gov/pubmed/22205196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2011.216 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|