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Performance Comparison of Various Maximum Likelihood Nonlinear Mixed-Effects Estimation Methods for Dose–Response Models

Estimation methods for nonlinear mixed-effects modelling have considerably improved over the last decades. Nowadays, several algorithms implemented in different software are used. The present study aimed at comparing their performance for dose–response models. Eight scenarios were considered using a...

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Detalhes bibliográficos
Main Authors: Plan, Elodie L., Maloney, Alan, Mentré, France, Karlsson, Mats O., Bertrand, Julie
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3385815/
https://ncbi.nlm.nih.gov/pubmed/22528503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-012-9349-2
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