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Performance of Three Estimation Methods in Repeated Time-to-Event Modeling

It is not uncommon that the outcome measurements, symptoms or side effects, of a clinical trial belong to the family of event type data, e.g., bleeding episodes or emesis events. Event data is often low in information content and the mixed-effects modeling software NONMEM has previously been shown t...

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Detalhes bibliográficos
Main Authors: Karlsson, Kristin E., Plan, Elodie L., Karlsson, Mats O.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032099/
https://ncbi.nlm.nih.gov/pubmed/21229340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-010-9248-3
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