Llwytho...

Convenient and Scalable Synthesis of Fmoc-Protected Peptide Nucleic Acid Backbone

The peptide nucleic acid backbone Fmoc-AEG-OBn has been synthesized via a scalable and cost-effective route. Ethylenediamine is mono-Boc protected, then alkylated with benzyl bromoacetate. The Boc group is removed and replaced with an Fmoc group. The synthesis was performed starting with 50 g of Boc...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Feagin, Trevor A., Shah, Nirmal I., Heemstra, Jennifer M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Hindawi Publishing Corporation 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400375/
https://ncbi.nlm.nih.gov/pubmed/22848796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/354549
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!