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Automated synthesis of backbone protected peptides

The synthesis of peptides rich in aggregation prone sequences can be improved with backbone protection. We report the automated introduction of backbone protection to a peptide. This new method was applied in a fully-automated synthesis, giving improved handling, quality and yield of several challen...

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Detalhes bibliográficos
Main Authors: Abdel-Aal, Abu-Baker M., Papageorgiou, George, Quibell, Martin, Offer, John
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4161149/
https://ncbi.nlm.nih.gov/pubmed/24938489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4cc03065f
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