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Automated synthesis of backbone protected peptides
The synthesis of peptides rich in aggregation prone sequences can be improved with backbone protection. We report the automated introduction of backbone protection to a peptide. This new method was applied in a fully-automated synthesis, giving improved handling, quality and yield of several challen...
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Main Authors: | , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
Royal Society of Chemistry
2014
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4161149/ https://ncbi.nlm.nih.gov/pubmed/24938489 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4cc03065f |
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