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Experimentally assessing molecular dynamics sampling of the protein native state conformational distribution

The acute sensitivity to conformation exhibited by amide hydrogen exchange reactivity provides a valuable test for the physical accuracy of model ensembles developed to represent the Boltzmann distribution of the protein native state. A number of molecular dynamics studies of ubiquitin have predicte...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Hernández, Griselda, Anderson, Janet S., LeMaster, David M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400181/
https://ncbi.nlm.nih.gov/pubmed/22425325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpc.2012.02.002
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