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False Discovery Rates of Protein Identifications: A Strike against the Two-Peptide Rule

Most proteomics studies attempt to maximize the number of peptide identifications and subsequently infer proteins containing two or more peptides as reliable protein identifications. In this study, we evaluate the effect of this “two-peptide” rule on protein identifications, using multiple search to...

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Dettagli Bibliografici
Autori principali: Gupta, Nitin, Pevzner, Pavel A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398614/
https://ncbi.nlm.nih.gov/pubmed/19627159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr9004794
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