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False Discovery Rates of Protein Identifications: A Strike against the Two-Peptide Rule

Most proteomics studies attempt to maximize the number of peptide identifications and subsequently infer proteins containing two or more peptides as reliable protein identifications. In this study, we evaluate the effect of this “two-peptide” rule on protein identifications, using multiple search to...

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Detalhes bibliográficos
Main Authors: Gupta, Nitin, Pevzner, Pavel A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398614/
https://ncbi.nlm.nih.gov/pubmed/19627159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr9004794
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