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Spectral Probabilities and Generating Functions of Tandem Mass Spectra: a Strike Against Decoy Databases
A key problem in computational proteomics is distinguishing between correct and false peptide identifications. We argue that evaluating the error rates of peptide identifications is not unlike computing generating functions in combinatorics. We show that the generating functions and their derivative...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2689316/ https://ncbi.nlm.nih.gov/pubmed/18597511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr8001244 |
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