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Target-Decoy Approach and False Discovery Rate: When Things May Go Wrong
The target-decoy approach (TDA) has done the field of proteomics a great service by filling in the need to estimate the false discovery rates (FDR) of peptide identifications. While TDA is often viewed as a universal solution to the problem of FDR evaluation, we argue that the time has come to criti...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3220955/ https://ncbi.nlm.nih.gov/pubmed/21953092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-011-0139-3 |
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