Fatty liver is associated with reduced SIRT3 activity and mitochondrial protein hyperacetylation

Acetylation has recently emerged as an important mechanism for controlling a broad array of proteins mediating cellular adaptation to metabolic fuels. Acetylation is governed, in part, by SIRTs (sirtuins), class III NAD(+)-dependent deacetylases that regulate lipid and glucose metabolism in liver du...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kendrick, Agnieszka A., Choudhury, Mahua, Rahman, Shaikh M., McCURDY, Carrie E., Friederich, Marisa, Van Hove, Johan L. K., Watson, Peter A., Birdsey, Nicholas, Bao, Jianjun, Gius, David, Sack, Michael N., Jing, Enxuan, Kahn, C. Ronald, Friedman, Jacob E., Jonscher, Karen R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398511/
https://ncbi.nlm.nih.gov/pubmed/21044047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20100791
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