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Sirt3 Impairment and SOD2 Hyperacetylation in Vascular Oxidative Stress and Hypertension
RATIONALE: Clinical studies have shown that Sirt3 expression declines by 40% by age 65 paralleling the increased incidence of hypertension and metabolic conditions further inactivate Sirt3 due to increased NADH and acetyl-CoA levels. Sirt3 impairment reduces the activity of a key mitochondrial antio...
Shranjeno v:
| izdano v: | Circ Res |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5562527/ https://ncbi.nlm.nih.gov/pubmed/28684630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.117.310933 |
| Oznake: |
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