Fatty liver is associated with reduced SIRT3 activity and mitochondrial protein hyperacetylation

Acetylation has recently emerged as an important mechanism for controlling a broad array of proteins mediating cellular adaptation to metabolic fuels. Acetylation is governed, in part, by SIRTs (sirtuins), class III NAD(+)-dependent deacetylases that regulate lipid and glucose metabolism in liver du...

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Detalhes bibliográficos
Main Authors: Kendrick, Agnieszka A., Choudhury, Mahua, Rahman, Shaikh M., McCURDY, Carrie E., Friederich, Marisa, Van Hove, Johan L. K., Watson, Peter A., Birdsey, Nicholas, Bao, Jianjun, Gius, David, Sack, Michael N., Jing, Enxuan, Kahn, C. Ronald, Friedman, Jacob E., Jonscher, Karen R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398511/
https://ncbi.nlm.nih.gov/pubmed/21044047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20100791
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