Novobiocin precipitates histones at concentrations normally used to inhibit eukaryotic type II topoisomerase.

At concentrations normally used to inhibit eukaryotic type II topoisomerase activity (100-1000 micrograms/ml) novobiocin binds core histones. Approximately 15 moles of novobiocin bind per mole of histone resulting in histone precipitation from solution in either 0.15 M or 2 M NaCl. The interaction b...

Descrizione completa

Dettagli Bibliografici

Pubblicato in:	Nucleic Acids Res
Autori principali:	Cotten, M, Bresnahan, D, Thompson, S, Sealy, L, Chalkley, R
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 1986
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC339807/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3714493/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/14.9.3671
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!