Wird geladen...

Novobiocin precipitates histones at concentrations normally used to inhibit eukaryotic type II topoisomerase.

At concentrations normally used to inhibit eukaryotic type II topoisomerase activity (100-1000 micrograms/ml) novobiocin binds core histones. Approximately 15 moles of novobiocin bind per mole of histone resulting in histone precipitation from solution in either 0.15 M or 2 M NaCl. The interaction b...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Cotten, M, Bresnahan, D, Thompson, S, Sealy, L, Chalkley, R
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1986
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC339807/
https://ncbi.nlm.nih.gov/pubmed/3714493
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!