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Plasma Neurofilament Heavy Chain Levels Correlate to Markers of Late Stage Disease Progression and Treatment Response in SOD1(G93A) Mice that Model ALS

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is an incurable neurodegenerative disorder characterised by progressive degeneration of motor neurons leading to death, typically within 3–5 years of symptom onset. The diagnosis of ALS is largely reliant on clinical assessment and electrophysiological...

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Sonraí Bibleagrafaíochta
Main Authors: Lu, Ching-Hua, Petzold, Axel, Kalmar, Bernadett, Dick, James, Malaspina, Andrea, Greensmith, Linda
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397981/
https://ncbi.nlm.nih.gov/pubmed/22815892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040998
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