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Cranial Irradiation Alters Dendritic Spine Density and Morphology in the Hippocampus

Therapeutic irradiation of the brain is a common treatment modality for brain tumors, but can lead to impairment of cognitive function. Dendritic spines are sites of excitatory synaptic transmission and changes in spine structure and number are thought to represent a morphological correlate of alter...

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Autors principals: Chakraborti, Ayanabha, Allen, Antino, Allen, Barrett, Rosi, Susanna, Fike, John R.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397939/
https://ncbi.nlm.nih.gov/pubmed/22815839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040844
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