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Cranial Irradiation Alters Dendritic Spine Density and Morphology in the Hippocampus

Therapeutic irradiation of the brain is a common treatment modality for brain tumors, but can lead to impairment of cognitive function. Dendritic spines are sites of excitatory synaptic transmission and changes in spine structure and number are thought to represent a morphological correlate of alter...

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Detalhes bibliográficos
Main Authors: Chakraborti, Ayanabha, Allen, Antino, Allen, Barrett, Rosi, Susanna, Fike, John R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397939/
https://ncbi.nlm.nih.gov/pubmed/22815839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040844
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