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Cranial Irradiation Alters Dendritic Spine Density and Morphology in the Hippocampus

Therapeutic irradiation of the brain is a common treatment modality for brain tumors, but can lead to impairment of cognitive function. Dendritic spines are sites of excitatory synaptic transmission and changes in spine structure and number are thought to represent a morphological correlate of alter...

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Главные авторы: Chakraborti, Ayanabha, Allen, Antino, Allen, Barrett, Rosi, Susanna, Fike, John R.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397939/
https://ncbi.nlm.nih.gov/pubmed/22815839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040844
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