Carbon Monoxide Mediates the Anti-apoptotic Effects of Heme Oxygenase-1 in Medulloblastoma DAOY Cells via K(+) Channel Inhibition

Tumor cell survival and proliferation is attributable in part to suppression of apoptotic pathways, yet the mechanisms by which cancer cells resist apoptosis are not fully understood. Many cancer cells constitutively express heme oxygenase-1 (HO-1), which catabolizes heme to generate biliverdin, Fe(...

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Main Authors: Al-Owais, Moza M. A., Scragg, Jason L., Dallas, Mark L., Boycott, Hannah E., Warburton, Philip, Chakrabarty, Aruna, Boyle, John P., Peers, Chris
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2012
Ábhair:
Signal Transduction
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397902/
https://ncbi.nlm.nih.gov/pubmed/22593583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.357012
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