Carbon Monoxide Mediates the Anti-apoptotic Effects of Heme Oxygenase-1 in Medulloblastoma DAOY Cells via K(+) Channel Inhibition

Tumor cell survival and proliferation is attributable in part to suppression of apoptotic pathways, yet the mechanisms by which cancer cells resist apoptosis are not fully understood. Many cancer cells constitutively express heme oxygenase-1 (HO-1), which catabolizes heme to generate biliverdin, Fe(...

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Detalhes bibliográficos
Main Authors: Al-Owais, Moza M. A., Scragg, Jason L., Dallas, Mark L., Boycott, Hannah E., Warburton, Philip, Chakrabarty, Aruna, Boyle, John P., Peers, Chris
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397902/
https://ncbi.nlm.nih.gov/pubmed/22593583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.357012
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