Carbon Monoxide Mediates the Anti-apoptotic Effects of Heme Oxygenase-1 in Medulloblastoma DAOY Cells via K(+) Channel Inhibition

Tumor cell survival and proliferation is attributable in part to suppression of apoptotic pathways, yet the mechanisms by which cancer cells resist apoptosis are not fully understood. Many cancer cells constitutively express heme oxygenase-1 (HO-1), which catabolizes heme to generate biliverdin, Fe(...

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Bibliografiske detaljer
Main Authors: Al-Owais, Moza M. A., Scragg, Jason L., Dallas, Mark L., Boycott, Hannah E., Warburton, Philip, Chakrabarty, Aruna, Boyle, John P., Peers, Chris
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2012
Fag:
Signal Transduction
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397902/
https://ncbi.nlm.nih.gov/pubmed/22593583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.357012
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