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Partial Enzymatic Deglycosylation Preserves the Structure of Cleaved Recombinant HIV-1 Envelope Glycoprotein Trimers

The trimeric envelope glycoprotein complex (Env) is the focus of vaccine development programs aimed at generating protective humoral responses to human immunodeficiency virus type 1 (HIV-1). N-Linked glycans, which constitute almost half of the molecular mass of the external Env domains, produce con...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Depetris, Rafael S., Julien, Jean-Philippe, Khayat, Reza, Lee, Jeong Hyun, Pejchal, Robert, Katpally, Umesh, Cocco, Nicolette, Kachare, Milind, Massi, Evan, David, Kathryn B., Cupo, Albert, Marozsan, Andre J., Olson, William C., Ward, Andrew B., Wilson, Ian A., Sanders, Rogier W., Moore, John P.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397850/
https://ncbi.nlm.nih.gov/pubmed/22645128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.371898
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