Lanean...
Watching DNA polymerase η make a phosphodiester bond
Native human DNA polymerase η, DNA and dATP were crystallized at pH 6.0 without Mg(2+). The polymerization reaction was initiated by exposing crystals to 1 mM Mg(2+) at pH 7.0, and stopped at various time points by freezing at 77 K for crystallographic analysis. The substrates and two Mg(2+) are ali...
Gorde:
| Egile Nagusiak: | , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2012
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3397672/ https://ncbi.nlm.nih.gov/pubmed/22785315 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11181 |
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