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DOMINANT-NEGATIVE EFFECT OF TRUNCATED MANNOSE 6-PHOSPHATE/INSULIN-LIKE GROWTH FACTOR II RECEPTOR SPECIES IN CANCER*
Oligomerization of the mannose 6-phosphate/insulin-like growth factor II receptor (M6P/IGF2R) is important for optimal ligand binding and internalization. M6P/IGF2R is a tumor suppressor gene that exhibits loss of heterozygosity and is mutated in several cancers. We tested the potential dominant-neg...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3396780/ https://ncbi.nlm.nih.gov/pubmed/22681933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2012.08652.x |
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