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Chronic pregabalin inhibits synaptic transmission between rat dorsal root ganglion and dorsal horn neurons in culture

In this study, we have examined the properties of synaptic transmission between dorsal root ganglion (DRG) and dorsal horn (DH) neurons, placed in co-culture. We also examined the effect of the anti-hyperalgesic gabapentinoid drug pregabalin (PGB) at this pharmacologically relevant synapse. The main...

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書目詳細資料
Main Authors: Hendrich, Janek, Bauer, Claudia S., Dolphin, Annette C.
格式: Artigo
語言:Inglês
出版: Landes Bioscience 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396689/
https://ncbi.nlm.nih.gov/pubmed/22627148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.19805
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