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Chronic pregabalin inhibits synaptic transmission between rat dorsal root ganglion and dorsal horn neurons in culture

In this study, we have examined the properties of synaptic transmission between dorsal root ganglion (DRG) and dorsal horn (DH) neurons, placed in co-culture. We also examined the effect of the anti-hyperalgesic gabapentinoid drug pregabalin (PGB) at this pharmacologically relevant synapse. The main...

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Détails bibliographiques
Auteurs principaux: Hendrich, Janek, Bauer, Claudia S., Dolphin, Annette C.
Format: Artigo
Langue:Inglês
Publié: Landes Bioscience 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396689/
https://ncbi.nlm.nih.gov/pubmed/22627148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.19805
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