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Chronic pregabalin inhibits synaptic transmission between rat dorsal root ganglion and dorsal horn neurons in culture

In this study, we have examined the properties of synaptic transmission between dorsal root ganglion (DRG) and dorsal horn (DH) neurons, placed in co-culture. We also examined the effect of the anti-hyperalgesic gabapentinoid drug pregabalin (PGB) at this pharmacologically relevant synapse. The main...

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Detalhes bibliográficos
Main Authors: Hendrich, Janek, Bauer, Claudia S., Dolphin, Annette C.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396689/
https://ncbi.nlm.nih.gov/pubmed/22627148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.19805
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