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Rac1 Activation Driven by 14-3-3ζ Dimerization Promotes Prostate Cancer Cell-Matrix Interactions, Motility and Transendothelial Migration

14-3-3 proteins are ubiquitously expressed dimeric adaptor proteins that have emerged as key mediators of many cell signaling pathways in multiple cell types. Its effects are mainly mediated by binding to selective phosphoserine/threonine proteins. The importance of 14-3-3 proteins in cancer have on...

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Hlavní autoři: Goc, Anna, Abdalla, Maha, Al-Azayzih, Ahmad, Somanath, Payaningal R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396618/
https://ncbi.nlm.nih.gov/pubmed/22808202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040594
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