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Dimerization Is Essential for 14-3-3ζ Stability and Function in Vivo
Members of the conserved 14-3-3 protein family spontaneously self-assemble as homo- and heterodimers via conserved sequences in the first four (αA-αD) of the nine helices that comprise them. Dimeric 14-3-3s bind conserved motifs in diverse protein targets involved in multiple essential cellular proc...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2804327/ https://ncbi.nlm.nih.gov/pubmed/19920133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.045989 |
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