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Determinants of 14-3-3σ Protein Dimerization and Function in Drug and Radiation Resistance

Many proteins exist and function as homodimers. Understanding the detailed mechanism driving the homodimerization is important and will impact future studies targeting the “undruggable” oncogenic protein dimers. In this study, we used 14-3-3σ as a model homodimeric protein and performed a systematic...

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Detalhes bibliográficos
Main Authors: Li, Zhaomin, Peng, Hui, Qin, Li, Qi, Jing, Zuo, Xiaobing, Liu, Jing-Yuan, Zhang, Jian-Ting
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814741/
https://ncbi.nlm.nih.gov/pubmed/24043626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.467753
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