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Critical role for calcium mobilization in activation of the NLRP3 inflammasome
The NLRP3 (nucleotide-binding domain, leucine-rich-repeat-containing family, pyrin domain-containing 3) inflammasome mediates production of inflammatory mediators, such as IL-1β and IL-18, and as such is implicated in a variety of inflammatory processes, including infection, sepsis, autoinflammatory...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3396518/ https://ncbi.nlm.nih.gov/pubmed/22733741 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117765109 |
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