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The NLRP3 inflammasome is critically involved in the development of bronchopulmonary dysplasia

The pathogenesis of bronchopulmonary dysplasia (BPD), a devastating lung disease in preterm infants, includes inflammation, the mechanisms of which are not fully characterized. Here we report that the activation of the NLRP3 inflammasome is associated with the development of BPD. Hyperoxia-exposed n...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Liao, Jie, Kapadia, Vishal S., Brown, L. Steven, Cheong, Naeun, Longoria, Christopher, Mija, Dan, Ramgopal, Mrithyunjay, Mirpuri, Julie, McCurnin, Donald C., Savani, Rashmin C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6215764/
https://ncbi.nlm.nih.gov/pubmed/26611836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9977
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