Llwytho...

Calcuim signaling and mitochondrial destabilization in the triggering of the NLRP3 inflammasome

The NLRP3 inflammasome is a cytosolic complex that activates Caspase-1, leading to maturation of IL-1β and IL-18 and induction of a pro-inflammatory cell death in sentinel cells of the innate immune system. Diverse stimuli have been shown to activate the NLRP3 inflammasome during infection and metab...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awdur: Horng, Tiffany
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041823/
https://ncbi.nlm.nih.gov/pubmed/24646829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2014.02.007
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