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Endothelial Nlrp3 Inflammasome Activation Associated with Lysosomal Destabilization during Coronary Arteritis

Inflammasomes play a critical role in the development of vascular diseases. However, the molecular mechanisms activating the inflammasome in endothelial cells and the relevance of this inflammasome activation is far from clear. Here, we investigated the mechanisms by which Nlrp3 inflammasome is acti...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: Chen, Yang, Li, Xiang, Boini, Krishna M., Pitzer, Ashley L., Gulbins, Erich, Zhang, Yang, Li, Pin-Lan
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4289419/
https://ncbi.nlm.nih.gov/pubmed/25450976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2014.11.012
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