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Endothelial Nlrp3 Inflammasome Activation Associated with Lysosomal Destabilization during Coronary Arteritis

Inflammasomes play a critical role in the development of vascular diseases. However, the molecular mechanisms activating the inflammasome in endothelial cells and the relevance of this inflammasome activation is far from clear. Here, we investigated the mechanisms by which Nlrp3 inflammasome is acti...

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Bibliographische Detailangaben
Veröffentlicht in:Biochim Biophys Acta
Hauptverfasser: Chen, Yang, Li, Xiang, Boini, Krishna M., Pitzer, Ashley L., Gulbins, Erich, Zhang, Yang, Li, Pin-Lan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4289419/
https://ncbi.nlm.nih.gov/pubmed/25450976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2014.11.012
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