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Trimethylamine-N-Oxide Instigates NLRP3 Inflammasome Activation and Endothelial Dysfunction

BACKGROUND/AIM: Plasma trimethylamine-N-oxide (TMAO), a product of intestinal microbial metabolism of dietary phosphatidylcholine has been recently associated with atherosclerosis and increased risk of cardiovascular diseases (CVD) in rodents and humans. However, the molecular mechanisms of how TMAO...

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Bibliografiska uppgifter
I publikationen:Cell Physiol Biochem
Huvudupphovsmän: Boini, Krishna M., Hussain, Tahir, Li, Pin-Lan, Koka, Saisudha
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828122/
https://ncbi.nlm.nih.gov/pubmed/29130962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000484623
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