Instigation of NLRP3 inflammasome activation and glomerular injury in mice on the high fat diet: role of acid sphingomyelinase gene

Ceramide has been reported to initiate inflammasome formation and activation in obesity and different pathological conditions. The present study was performed to explore the role of acid sphingomyelinase (Asm) in the development of high fat diet (HFD)-induced inflammasome and activation and conseque...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Boini, Krishna M., Xia, Min, Koka, Saisudha, Gehr, Todd W., Li, Pin-Lan
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4951349/
https://ncbi.nlm.nih.gov/pubmed/26980705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8023
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