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Choline Treatment Activates NLRP3 Inflammasome Formation and Leads to Endothelial Dysfunction in Mice

OBJECTIVES: Choline and other trimethylamine-containing nutrients are metabolized by gut microbiota into Trimethylamine N-oxide (TMAO), which is involved in the pathogenesis of various cardiovascular diseases. The present study was designed to investigate the relation between dietary choline and end...

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Detalhes bibliográficos
Publicado no:Curr Dev Nutr
Main Authors: Koka, Saisudha, Puchchakayala, Goverdhan, Boini, Krishna
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7257028/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cdn/nzaa040_044
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