Structural basis of inhibition of Mycobacterium tuberculosis DprE1 by benzothiazinone inhibitors

Resistance against currently used antitubercular therapeutics increasingly undermines efforts to contain the worldwide tuberculosis (TB) epidemic. Recently, benzothiazinone (BTZ) inhibitors have shown nanomolar potency against both drug-susceptible and multidrug-resistant strains of the tubercle bac...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Batt, Sarah M., Jabeen, Talat, Bhowruth, Veemal, Quill, Lee, Lund, Peter A., Eggeling, Lothar, Alderwick, Luke J., Fütterer, Klaus, Besra, Gurdyal S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2012
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396498/
https://ncbi.nlm.nih.gov/pubmed/22733761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1205735109
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items