Structural basis of inhibition of Mycobacterium tuberculosis DprE1 by benzothiazinone inhibitors

Resistance against currently used antitubercular therapeutics increasingly undermines efforts to contain the worldwide tuberculosis (TB) epidemic. Recently, benzothiazinone (BTZ) inhibitors have shown nanomolar potency against both drug-susceptible and multidrug-resistant strains of the tubercle bac...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Batt, Sarah M., Jabeen, Talat, Bhowruth, Veemal, Quill, Lee, Lund, Peter A., Eggeling, Lothar, Alderwick, Luke J., Fütterer, Klaus, Besra, Gurdyal S.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2012
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396498/
https://ncbi.nlm.nih.gov/pubmed/22733761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1205735109
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki