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Calcium homeostasis modulator 1 (CALHM1) is the pore-forming subunit of an ion channel that mediates extracellular Ca(2+) regulation of neuronal excitability

Extracellular Ca(2+) (Ca(2+) (o)) plays important roles in physiology. Changes of Ca(2+)(o) concentration ([Ca(2+)](o)) have been observed to modulate neuronal excitability in various physiological and pathophysiological settings, but the mechanisms by which neurons detect [Ca(2+)](o) are not fully...

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Detalhes bibliográficos
Main Authors: Ma, Zhongming, Siebert, Adam P., Cheung, King-Ho, Lee, Robert J., Johnson, Brian, Cohen, Akiva S., Vingtdeux, Valérie, Marambaud, Philippe, Foskett, J. Kevin
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396471/
https://ncbi.nlm.nih.gov/pubmed/22711817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1204023109
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