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How do taste cells lacking synapses mediate neurotransmission? CALHM1, a voltage-gated ATP channel

CALHM1 was recently demonstrated to be a voltage-gated ATP-permeable ion channel and to serve as a bona fide conduit for ATP release from sweet-, umami-, and bitter-sensing type II taste cells. Calhm1 is expressed in taste buds exclusively in type II cells and its product has structural and function...

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Detalhes bibliográficos
Main Authors: Taruno, Akiyuki, Matsumoto, Ichiro, Ma, Zhongming, Marambaud, Philippe, Foskett, J. Kevin
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3981604/
https://ncbi.nlm.nih.gov/pubmed/24105910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201300077
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