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Structural dynamics of the ΔE22 (Osaka) familial Alzheimer's disease-linked amyloid β-protein

A familial form of Alzheimer disease (AD) recently was described in a kindred in Osaka, Japan. This kindred possesses an amyloid β-protein (Aβ) precursor mutation within the Aβ coding region that results in the deletion of Glu22 (ΔE22). We report here results of studies of [ΔE22]Aβ40 and ΔE22Aβ42 th...

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Detalhes bibliográficos
Main Authors: Inayathullah, Mohammed, Teplow, David B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396427/
https://ncbi.nlm.nih.gov/pubmed/21668291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/13506129.2011.580399
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