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Predict impact of single amino acid change upon protein structure
BACKGROUND: Amino acid point mutations (nsSNPs) may change protein structure and function. However, no method directly predicts the impact of mutations on structure. Here, we compare pairs of pentamers (five consecutive residues) that locally change protein three-dimensional structure (3D, RMSD>0...
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| Glavni autori: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2012
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3395892/ https://ncbi.nlm.nih.gov/pubmed/22759652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-S4-S4 |
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