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Correlating protein function and stability through the analysis of single amino acid substitutions
BACKGROUND: Mutations resulting in the disruption of protein function are the underlying causes of many genetic diseases. Some mutations affect the number of expressed proteins while others alter the activity on a per-molecule basis. Single amino acid substitutions as caused by non-synonymous Single...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2745590/ https://ncbi.nlm.nih.gov/pubmed/19758472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-10-S8-S8 |
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