Evaluating the predictions of the protein stability change upon single amino acid substitutions for the FXN CAGI5 challenge

Frataxin (FXN) is a highly-conserved protein found in prokaryotes and eukaryotes that is required for an efficient regulation of cellular iron homeostasis. Experimental evidence associates amino acid substitutions of the frataxin to Friedreich Ataxia, a neurodegenerative disorder. Recently, new ther...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Hum Mutat
Autors principals: Savojardo, Castrense, Petrosino, Maria, Babbi, Giulia, Bovo, Samuele, Corbi-Verge, Carles, Casadio, Rita, Fariselli, Piero, Folkman, Lukas, Garg, Aditi, Karimi, Mostafa, Katsonis, Panagiotis, Kim, Philip M., Lichtarge, Olivier, Martelli, Pier Luigi, Pasquo, Alessandra, Pal, Debnath, Shen, Yang, Strokach, Alexey V., Turina, Paola, Zhou, Yaoqi, Andreoletti, Gaia, Brenner, Steven, Chiaraluce, Roberta, Consalvi, Valerio, Capriotti, Emidio
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744327/
https://ncbi.nlm.nih.gov/pubmed/31209948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.23843
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars